Research Journal of Pharmacognosy and Phytochemistry

Ravindra Singh ¹, Aakanksha Tiwari ¹

Affiliations
1 Department of Biological Science, Mahatma Gandhi Chitrakoot Gramodaya Vishwavidyalya, Chitrakoot, Satna (M.P) Pin-488334, IN

Abstract

Adhatoda vasica belonging to Acanthaceae family, commonly known as Adosa, is found in many regions of India and throughout the world, with a multitude of uses in traditional Ayurveda. Vasica is most well-known for its effectiveness in treating respiratory conditions and are highly demandable in pharmaceutical industries. The compound isolated from ethyl acetate fraction of Adhatoda vasica flowers extract has a significant antibacterial activity against bacteria and fungi. Four bacterial strains like S. typhi, E. coli, E. faecalis and B. cereus and two fungal strains such as C. lunata and C.albicans were tested by using disc diffusion method. The anti bacterial activity of the compound isolated from ethyl acetate fraction is almost comparable with the standard Chloramphenicol and the anti-fungal activity of the compound isolated from ethyl acetate fraction is almost comparable with the standard Fluconazole. These are the drugs from Adhatoda vasica flowers that either destroy or inhibit the growth of bacteria and fungi. It has also the ability to prevent or treat bacterial and fungal infections. Further studies are highly needed for future drug development. The present research aims to compile medicinal values of Adhatoda vasica flowers generated through the research activity using modern scientific approaches and innovative scientific tools.

Keywords

Adhatoda vasica, Pharmacology, Asthma, Traditional Medicine.

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Ravi Sunder Prajapati ¹, G. P. Richhariya ², I. P. Tripathi ¹, Ravindra Singh ¹, Manoj Tripathi ³

Affiliations
1 Mahatma Gandhi Chitrakoot Gramaodaya Vishwavidyalaya, Chitrakoot, Satna (M.P.), IN
2 Department of Botany, Government Post Graduate College, Satna (M.P.), IN
3 Arogyadham, Deendayal Research Institute, Chitrakoot, Satna (M.P.), IN

Abstract

Medicinal plants have been found useful in the cure of a number of diseases including bacterial diseases. Nimba is a very useful medicinal plant in the sub-continent and each part of the plant has medicinal properties. Almost every part of the plant has been in use since ancient times to treat a number of human ailments and also as a household pesticide. The extract from bark, leaves, fruits and ischolar_main have been used to control leprosy, intestinal helminthiasis and respiratory disorders in children. Flavonoids, flavonoglycosides, dihydrochalcones, tannins and others are also important constituents of bark, leaves, fruits and flowers of Nimba. Present study aimed development and establishment of the HPTLC fingerprint profile and phytochemical screening of Nimba leaf and stem bark.

Keywords

Azadirachta indica, Phytochemical Analysis, HPTLC Fingerprinting.

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Ravindra Singh ¹, Aakanksha Tiwari ¹

Affiliations
1 Department of Biological Science, Mahatma Gandhi Chitrakoot Gramodaya Vishwavidyalaya, Chitrakoot-488334, Satna (M.P), IN

Abstract

Clerodendrum serratum is a shrub which is not much branched with stems. The ischolar_main of the plant is attributed with various activities like anti-inflammatory, digestive and carminative and many more. It is used to treat the conditions like inflammations, anorexia, cough, asthma, hiccough, tubercular glands, skin diseases etc. Various minerals like Na, Mg, Al, Ca etc. saponins, terpenoids, D-mannitol are the phytoconstituents present in the plant. Research works are carried out to study the pharmacognostic, physicochemical, hepatoprotective, anti-oxidant, anti-inflammatory, analgesic, antiasthmatic and various other activities. Clinical trial was also done in patients of Tamaka shwasa (Bronchial asthma). Thus, this paper highlights the various pharmacological activities of Clerodendrum serratum and its further scope for clinical utility.

Keywords

Cleodendrum serratum, Pharmacology, Asthma, Traditional Medicine.

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